HomeAboutFaculty DirectoryONG Choon Nam

ONG Choon Nam


  • NUS Saw Swee Hock School of Public Health (Primary)
  • Director, NUS Environmental Research Institute (NERI)

Research Areas:

  • My main research interest is on Environmental Health Sciences, Identification of Biomarkers Using Metabolomics and Environmental Toxicology. More than 300 peer-reviewed academic articles were published with over 18,500 citations, and an H-index of 79.

Click here for the full list. 

Teaching Areas:

  • Environment and Health
  • Toxicology

Academic/Professional Qualifications:

  • BSc, Nanyang University, 1972
  • MSc, University of London, 1974
  • PhD, Manchester University, 1977

Awards/Honours (Post-PhD):

  • 2002    AstraZeneca International Award, Society of Toxicology (USA)
  • 2004    Special Commendation Award (SARS Education), NUS
  • 2005    Outstanding Science Alumni Award, NUS
  • 2006    Service to Education Award, Ministry of Education
  • 2008    Research Excellence Award, NUHS
  • 2008    Nanyang Alumni Achievement Award, NTU
  • 2016    Outstanding Mentor Award, Singapore Medical Association Charity Fund

Professional/Consulting Activities:

  • As a consultant to the World Health Organization (WHO) since 1998 and involved in 12 of its Health Criteria publications.
  • Served as an editorial board member of several international journals on environment and sustainability. Currently an Associate Editor of Encyclopedia on Environmental Health.
  • As a Scientific Advisor of the China Center of Disease Control and Prevention (China- CDC).
  • Advisor to the OECD and US National Water Research Institute.
  • Member, WHO Guidelines for Drinking-Water Quality Expert Panel since 2003.
  • Chairman, International Expert Panel on the NEWater study.

Major Publications:

  • Lu et al. Acetylcarnitine Is a Candidate Diagnostic and Prognostic Biomarker of Hepatocellular Carcinoma. Cancer Res. 2016 15; 76: 2912-20.
  • Ding WX, Shen HM, Ong CN. Critical role of reactive oxygen species and mitochondrial permeability transition in microcystin-induced rapid apoptosis in rat hepatocytes. Hepatology. 2000; 32: 547-55.
  • Ding WX, Shen HM, Ong CN. Microcystic cyanobacteria extract induces cytoskeletal disruption and intracellular glutathione alteration in hepatocytes. Environ Health Perspect. 2000; 108: 605-9.
  • Huang Q, et al. Emodin inhibits tumor cell adhesion through disruption of the membrane lipid Raft-associated integrin signaling pathway. Cancer Res. 2006; 66: 5807-15.
  • Yuan JM et al. Prediagnostic level of serum retinol in relation to reduced risk of hepatocellular carcinoma. J Natl Cancer Inst. 2006; 98: 482-90.
  • Isabelle M, et al. Antioxidant activity and profiles of common vegetables in Singapore. Food Chemistry 2010; 120, 993-1003.
  • Huang SM, et al. Metabolic studies show dose-dependent toxicity induced by SiO2 nanoparticles in human fetal lung fibroblasts. Advanced healthcare materials 2012; 1:779-784.
  • Xu F et al. Metabolic signature shift in type 2 diabetes mellitus revealed by mass spectrometry-based metabolomics. J Clin Endocrinol Metab. 2013; 98:E1060-5.
  • Ho WE, et al. Metabolomics reveals altered metabolic pathways in experimental asthma. Am J Respir Cell Mol Biol. 2013; 48: 204-11.
  • Gao Y, et al. Indentifying early urinary metabolic changes with long-term environmental exposure to cadmium using LC-MS based metabolomics. Environmental science & technology 2014; 48: 6409-6418.

Media Coverage:

See also http://www.nus.edu.sg/neri/

Tel (65) 6516 4982
Fax (65) 67791489
Email ephocn@nus.edu.sg or eridir@nus.edu.sg


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