HomeResearchCentre for Environmental and Occupational Health Research (CEOHR)

Centre for Environmental and Occupational Health Research (CEOHR)

Aim

The main mission of the Centre for Environmental and Occupational Health Research is to elucidate and prevent environmental and occupational related health problems.

Research Foci

The Centre’s current research foci include the detection and control of environmental and occupational diseases, carcinogenesis and chemoprevention, oxidative stress and antioxidants, and metabolomics. CEOHR also conducts research on the identification of biomarkers for the School’s Environmental and Occupational Health Studies, especially on how lifestyle and diets may affect chronic diseases such as diabetes and cardiovascular diseases.

CEOHR collaborates with various government agencies and industries on environmental surveillance to examine the impact of haze and air quality that may affect Singapore and the region.  The Centre also teams up with other universities and institutions working on food securities, and its role is to identify the beneficial effects of nutrients of local leafy vegetables.

Main Research Areas

  • Detection and Control of Environmental and Occupational Diseases
  • Carcinogenesis and Chemoprevention
  • Oxidative Stress and Antioxidants
  • Identification of biomarkers for Environmental and Occupational health studies

Investigators:

Research Staff:

  • Dr Lu Yonghai
  • Dr Lim Swee Ling
  • Ms Zou Li

Key Research Partners

The Centre conducts research in areas concerning chemical safety, and environmental and occupational health through close collaborations with the NUS Environmental Research Institute (NERI), Duke-NUS Graduate Medical School, Singapore–MIT Alliance and Research Technology (SMART), China Center for Disease Control, Osaka University in Japan, Shanghai Jiao Tong University, Fudan University, Wuhan University and other institutions in China.  The Centre also has close collaborations with the Massachusetts Institute of Technology (MIT) and University of Pittsburgh in the US over the past 10 years.

The Centre also collaborates with petrochemical industries on the detection of hazardous chemicals in petroleum.

Consultancy and Laboratory Services

The Centre provides advice, consultancy and laboratory services to research institutions, such as the World Health Organization and industries.

Major laboratory activities

  1. Environmental Monitoring of Dust, Metal Fume, Oil Mist and Organic Solvents
  2. Analysis of Heavy Metals & Trace Elements in Biological Sample: Lead (Pb), Cadmium (Cd) and Mercury (Hg) etc., using Atomic Absorption Spectrophotometer
  3. Analysis of Volatile Organic Solvent Vapors including Hydrocarbons and Halogenated Hydrocarbons using Gas Chromatograph with FID/ECD/MS Detection
  4. Analysis of Urinary Mandelic Acid, S-phenylmercapturic acid, t,t-Muconic Acid, Hippuric Acid and Methyl-Hippuric Acid etc., using High Performance Liquid Chromatography (HPLC)
  5. Analysis of Serum/Plasma including Vitamin A, E & C, Carotenoids, fatty acids, oxidative lipids such as oxylipins, Homocysteine, UBQ10 and VMA/HVA etc., using High Performance Liquid Chromatography (HPLC), Gas Chromatography Mass Spec and Liquid Chromatography- Mass Spec

All the above laboratory services are supported with the following Quality Control Proficiency Testing Programmes.  The Centre also closely follows the standards and guidelines of American Conference of Governmental Industrial Hygienists (ACGIH):

  • German External Quality Assurance Scheme for Organic Solvents Metabolites in Urine
  • AIHA Proficiency Analytical Testing (BAPAT) Programme - Asbestos Analysis and Identification in Bulk Sample
  • AIHA Proficiency Analytical Testing (IHPAT) Programme - Industrial Hygiene Organic Solvents

 

Saw Swee Hock School of Public Health
 
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National University of Singapore
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#10-01
Singapore 117549
 
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